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Senior consultant in medicinal chemistry and bioscience licensing and patenting with broad background in both academic and
industrial environments. Currently partnered for pharmaceutical licensing by Transpect, Inc. (Yokohama) and its Japanese pharmaceutical
company clients.
Registered Patent Agent and pharmaceutical/biotechnology/medicinal chemistry patent consultant.
President, Intellepharm, Inc. (1996- ).
As Senior Vice President, ImmunoPharmaceutics (1989-1995) responsible
for R&D strategic planning, management, funding development, and strategic alliances for an early stage NCE drug discovery
company. These activities lead to the design and synthesis of Thelin® (sitaxsentan), a picomolar,
subtype selective endothelin A receptor antagonist marketed by Pfizer for pulmonary arterial hypertension (PAH) in
the EU and Canada.
As Vice-President for Research, Allergan (1982-1988) developed strategy, built
and managed R&D group that discovered Tazorac® (tazarotene) for acne/psoriasis and Alphagan® (brimonidlne) for
glaucoma, and Lumigan® (bimatoprost) for glaucoma.
As University of California department chairman,
built major academic center and graduate department of drug design.
International authority in medicinal
chemistry with 100+ publications and patents supported by 20 years of NIH grant support.
Elected Fellow,
American Association of Pharmaceutical Scientists. Elected Fellow, American Association for the Advancement of Science.
Elected Member, United States Pharmacopoeia Committee of Revision (1990-2010).
Adjunct
Professor of Medicinal Chemistry, University of Southern California, Los Angeles, (1988-2008).
Faculty,
Drew University Residential Course in Medicinal Chemistry, (1998-2008).
Editor, "Burger's Medicinal
Chemistry and Drug Discovery", (Vol. 1-5), Wiley (1995-7).
B.S., Pharmacy, University of California,
Berkeley. Ph.D., Pharmaceutical Chemistry, University of California, Berkeley. Post-doctoral Scholar, Department of
Chemistry, University of Virginia. Sabbatical Fellowship with Nobel Laureate Prof. Sir E.B. Chain, Department of Biochemistry,
and Nobel Laureate Prof. Sir D.H.R. Barton, Department of Chemistry, Imperial College, London.
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